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An insulin syringe is chosen on three things: the insulin concentration, the largest dose you draw up and the needle. On the pack you recognize them by the volume (“1 ml”, “0.5 ml”) and by the needle gauge and length (“29G × 13 mm”). This guide explains what each one means, what the international recommendations say about needle length, how pen needles are used and which syringes and needles the catalog currently has. The dose, the needle length and the injection technique are set by the diabetes doctor or the diabetes nurse.
“U-100” means 100 units of insulin in one milliliter. It is the standard concentration, and insulin syringes are graduated in units precisely for it. The basic rule is that the syringe must be marked for the same concentration as the insulin: the FDA-approved label of a U-100 human insulin calls for a syringe marked for U-100 preparations. If the syringe scale does not match the insulin, the dose you read on the syringe no longer matches the dose you inject.
Concentrated insulins, with more than 100 units per milliliter, are not drawn from a pen with a syringe. The American Diabetes Association guidance for school nurses warns that transferring them to a different device, for example from a pen into a syringe, can lead to overdose and severe hypoglycemia. For the parts of a syringe, the Luer tip and safe injection, read the guide Medical Syringes and Needles.
With U-100, each unit takes up a hundredth of a milliliter, so the syringe volume tells you directly how many units fit in it. Two columns matter when you order: the capacity and what one graduation is worth.
| Volume | Capacity at U-100 | One graduation, on catalog syringes | In the catalog |
|---|---|---|---|
| 0.3 ml | 30 units | – | not at present |
| 0.5 ml | 50 units | check on the barrel | yes fixed 30G needle |
| 1 ml | 100 units | 0.01 ml (1 unit) on the syringe with a 23G needle; 0.02 ml (2 units) on the one with a 25G needle | yes several versions |
Choose the volume by the largest dose you draw up: a 0.5 ml syringe holds at most 50 units, so for a larger dose you need the 1 ml syringe. When you switch to a new model, count the graduations between two numbers to find out what one is worth: in the catalog, the same 1 ml capacity comes graduated in single units and in steps of two units.
The insulin syringes in the catalog come in two designs. The difference shows on the pack as “fixed needle” or “embedded needle” versus “detachable needle”:
The insulin syringes in the catalog are sterile and have a rubber plunger; those whose product sheet states the method are sterilized with ethylene oxide. For the 0.5 ml syringe and the 1 ml syringe with a detachable 29G needle, the product sheet states that the plunger seal is made of natural rubber.
In 2016, an international expert group (FITTER) published new insulin delivery recommendations in Mayo Clinic Proceedings. On needles, their conclusion is clear: the shortest ones, the 4 mm pen needle and the 6 mm syringe needle, are safe, effective and less painful, and they are the first choice. The BD press release that accompanied the publication states that the recommendation applies to all patients who inject insulin, regardless of age, sex or body size.
The needles in the catalog are longer than the first-choice needles:
| What the catalog has | Gauge | Needle length |
|---|---|---|
| Pen needles | 29G | 12 mm |
| 1 ml syringes with a fixed needle | 29G or 27G | 13 mm |
| 1 ml syringe with a detachable needle | 25G | 16 mm |
| 1 ml syringe with a detachable needle | 23G | 25 mm |
4 mm pen needles and syringes with a 6 mm needle are not in the catalog at present. The right length and technique for you are set by the diabetes doctor or the diabetes nurse. The needle color code by gauge is in the glossary of sizes and colors.
Pen needles fit onto the insulin pen and are changed for every injection. The catalog has 29G × 12 mm pen needles, made of silicone-lubricated stainless steel, color-coded red, in boxes of 100. Their product sheet lists them as compatible with universal insulin pens; before you order, check the pen's instructions for the needles it accepts.
The syringe and the insulin have the same concentration. Veterinary insulin at 40 units/ml needs U-40 syringes.
Set by the largest dose. At U-100, 0.5 ml means at most 50 units.
How thin the needle is. In the catalog, 23G to 30G on syringes and 29G on pen needles.
FITTER puts 4 mm on pens and 6 mm on syringes first; your length is set by the doctor.
The FITTER recommendations describe lipohypertrophy, the lumps of fatty tissue that form under the skin at sites used often, as a frequent complication of therapy: insulin is absorbed unevenly from these areas, and injections are not given there. Correct rotation of injection sites helps prevent them. The BD press release also sums up the recommendation to use pen needles and syringes only once, because reusing needles is not an optimal injection practice.
In a medical practice, used needles go into yellow rigid plastic containers for sharps waste, as required by the technical norms approved by Romanian Ministry of Health Order 1226/2012 (art. 17). The catalog has containers from 1 to 12 liters. For labeling, filling and how long you keep a container in the practice, read the guide Medical waste in the practice. At home, too, used needles are safer in a rigid container with a lid than in a trash bag.
| Situation | What to check | In the catalog |
|---|---|---|
| U-100 insulin from a vial, doses up to 50 units | 0.5 ml U-100 syringe | 0.5 ml syringe with a fixed 30G needle |
| U-100 insulin from a vial, doses above 50 units | 1 ml U-100 syringe | 1 ml syringes with a fixed 29G or 27G needle |
| You want to choose the needle separately | Syringe with a needle tip | 1 ml syringe without a needle or with a detachable needle |
| Insulin pen | Needles compatible with the pen, length set by the doctor | 29G × 12 mm pen needles |
| Veterinary insulin at 40 units/ml | U-40 syringes or the VetPen | not in the catalog |
| Medical practice | Yellow sharps container | Containers of 1–12 liters |
Test strips for blood glucose meters are in the blood glucose test strips category. Orders placed by 2 p.m. usually ship the same day, and delivery takes 1–2 working days.
U-100 syringes of 0.5 and 1 ml, with a fixed or detachable needle, 29G × 12 mm pen needles and sharps waste containers, in the Prima Shop catalog.
With U-100 insulin, 100 units, because one milliliter contains 100 units. The 0.5 ml syringe holds 50 units and the 0.3 ml syringe 30.
Not for insulin at 40 units/ml. Caninsulin, for example, is given only with U-40 syringes or the VetPen, according to the product information published by the VMD. With a U-100 syringe, at the same mark you would draw 2.5 times fewer units.
The 2016 FITTER recommendations consider the shortest needles, 4 mm on pens and 6 mm on syringes, safe, effective and less painful, and put them first. The right length for you is set by your doctor.
The FITTER recommendations limit pen needles and syringes to a single use, because reusing them is not an optimal injection practice. Fit a new needle for every injection.
They are called lipohypertrophy and form at sites used often. The FITTER recommendations state that insulin is absorbed unevenly from them, that you should not inject there and that correct site rotation helps prevent them.
0.5 ml (50 units) syringes with a fixed 30G needle, 1 ml syringes with a fixed 29G or 27G needle, with a detachable 29G, 25G or 23G needle and without a needle, plus 29G × 12 mm pen needles. 0.3 ml syringes are not in the catalog at present.
Diferența dintre recipientul de coprocultură simplu și cel cu mediu de transport (gel), cum recoltezi scaunul cu spatula, urina în urocultor și exudatul faringian, plus cum păstrezi probele până la laborator.
Every code on the pack in one place: needle gauge and hub colors, IV cannulas, CH/Fr catheter sizes, USP sutures, glove sizes, blood tube stoppers and U-100 insulin syringes, with tables.
What vacutainer cap colors mean, which additive each tube holds, the order of draw under CLSI GP41 and EFLM, how many inversions each tube needs and what to check on the label.
The recommendations on the home page help you find the right products for your practice, clinic or business faster.
